US 12,070,614 B2
Apparatus and method for magnetic particle imaging and thermotherapy fusion based on field-free line inertial scanning
Jie Tian, Beijing (CN); Jie He, Beijing (CN); Hui Hui, Beijing (CN); Jing Zhong, Beijing (CN); Yu An, Beijing (CN); and Zhenchao Tang, Beijing (CN)
Assigned to Beihang University, (CN)
Filed by BEIHANG UNIVERSITY, Beijing (CN)
Filed on Mar. 1, 2023, as Appl. No. 18/115,888.
Prior Publication US 2023/0338740 A1, Oct. 26, 2023
Int. Cl. A61N 1/40 (2006.01); A61B 5/0515 (2021.01); A61N 2/02 (2006.01)
CPC A61N 1/406 (2013.01) [A61B 5/0515 (2013.01); A61N 2/02 (2013.01)] 8 Claims
OG exemplary drawing
 
1. An apparatus for magnetic particle imaging and thermotherapy fusion based on field-free line inertial scanning, comprising:
a magnetic body group;
an induction coil;
a living body bed;
a control device;
a display device; and
an image processing device,
wherein the magnetic body group further comprises a long curved magnetic body pair and a cylindrical magnetic body,
wherein the long curved magnetic body pair comprises two long curved magnetic bodies, each of the two long curved magnetic bodies comprises a first structural member, a second structural member and a third structural member,
wherein the first structural member and the third structural member are U-shaped magnetic bodies,
wherein the second structural member further comprises two symmetrical arc-shaped magnetic bodies prepared using a preset curvature,
wherein the first structural member is parallel to the third structural member,
wherein a plane where the second structural member is located is perpendicular to a plane where the first structural member is located,
wherein two ends of the second structural member are respectively connected to open ends of the U-shaped magnetic bodies of the first structural member and the third structural member,
wherein shapes of the long curved magnetic bodies are the same,
wherein the long curved magnetic bodies are parallel to each other,
wherein central axes of the long curved magnetic bodies are collinear,
wherein closed ends of the first structural member or the third structural member of the long curved magnetic bodies of the long curved magnetic body pair are opposite of each other,
wherein the cylindrical magnetic body is arranged in a space surrounded by the long curved magnetic body pair,
wherein an axis of the cylindrical magnetic body is perpendicular to a central axis of the long curved magnetic body pair,
wherein the long curved magnetic body pair is configured to simultaneously receive a current component in a same direction and a current component in a reverse direction for generating and translating a field-free line,
wherein through changing the current component in the same direction, a biasing position of the field-free line is adjusted,
wherein through changing the current component in the reverse direction, a gradient of a gradient magnetic field is adjusted,
wherein the cylindrical magnetic body is configured to receive a direct current component and a radiofrequency current component,
wherein the cylindrical magnetic body is configured to receive the direct current component for adjusting a depth of the field-free line in an axial direction of the cylindrical magnetic body,
wherein the cylindrical magnetic body is configured to receive the radio frequency current component for induction heating of magnetic nanoparticles in a field-free region,
wherein the control device is used to control current variation and mechanical rotation of the long curved magnetic body pair, current variation of the cylindrical magnetic body, and moving depth of the living body bed, according to a preset control command, thereby realizing translation, rotation and serial-layer scanning of the field-free line, realizing a scanning and imaging of a target living body and a positioning of the field-free line, and allowing thermotherapy to be performed on a preset area of the target living body.