US 12,070,593 B2
Vagal nerve stimulation for treating dopamine-related conditions
Bruce J. Simon, Santa Fe, NM (US); Joseph P. Errico, Palm Beach Gardens, FL (US); and John T. Raffle, Austin, TX (US)
Assigned to ELECTROCORE, INC, Rockaway, NJ (US)
Filed by ELECTROCORE, INC, Rockaway, NJ (US)
Filed on Mar. 6, 2023, as Appl. No. 18/117,542.
Application 16/540,435 is a division of application No. 14/992,921, filed on Jan. 11, 2016, granted, now 10,384,061, issued on Aug. 20, 2019.
Application 14/229,894 is a division of application No. 13/109,250, filed on May 17, 2011, granted, now 8,676,330, issued on Mar. 18, 2014.
Application 14/229,894 is a division of application No. 13/075,746, filed on Mar. 30, 2011, granted, now 8,874,205, issued on Oct. 28, 2014.
Application 14/229,894 is a division of application No. 13/024,727, filed on Feb. 10, 2011, granted, now 9,089,719, issued on Jul. 28, 2015.
Application 18/117,542 is a continuation of application No. 17/702,051, filed on Mar. 23, 2022, granted, now 11,623,080.
Application 17/702,051 is a continuation of application No. 17/461,886, filed on Aug. 30, 2021, granted, now 11,623,079.
Application 17/461,886 is a continuation of application No. 16/540,435, filed on Aug. 14, 2019, granted, now 11,297,445, issued on Apr. 5, 2022.
Application 14/992,921 is a continuation of application No. 14/229,894, filed on Mar. 29, 2014, granted, now 9,233,246, issued on Jan. 12, 2016.
Application 13/109,250 is a continuation in part of application No. 13/005,005, filed on Jan. 12, 2011, granted, now 8,868,177, issued on Oct. 21, 2014.
Application 13/005,005 is a continuation in part of application No. 12/964,050, filed on Dec. 9, 2010, abandoned.
Application 14/229,894 is a continuation in part of application No. 12/859,568, filed on Aug. 19, 2010, granted, now 9,037,247, issued on May 19, 2015.
Application 12/859,568 is a continuation in part of application No. 12/612,177, filed on Nov. 4, 2009, granted, now 8,041,428, issued on Oct. 18, 2011.
Application 12/859,568 is a continuation in part of application No. 12/408,131, filed on Mar. 20, 2009, granted, now 8,812,112, issued on Aug. 19, 2014.
Application 12/612,177 is a continuation in part of application No. 11/592,095, filed on Nov. 2, 2006, granted, now 7,725,188, issued on May 25, 2010.
Application 12/408,131 is a continuation in part of application No. 11/591,340, filed on Nov. 1, 2006, granted, now 7,747,324, issued on Jun. 29, 2010.
Claims priority of provisional application 61/471,405, filed on Apr. 4, 2011.
Claims priority of provisional application 61/451,259, filed on Mar. 10, 2011.
Claims priority of provisional application 61/415,469, filed on Nov. 19, 2010.
Claims priority of provisional application 60/814,313, filed on Jun. 16, 2006.
Claims priority of provisional application 60/814,312, filed on Jun. 16, 2006.
Claims priority of provisional application 60/786,564, filed on Mar. 28, 2006.
Claims priority of provisional application 60/772,361, filed on Feb. 10, 2006.
Claims priority of provisional application 60/736,002, filed on Nov. 10, 2005.
Claims priority of provisional application 60/736,001, filed on Nov. 10, 2005.
Prior Publication US 2023/0201569 A1, Jun. 29, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 1/04 (2006.01); A61N 1/36 (2006.01); A61N 1/40 (2006.01); A61N 2/00 (2006.01); A61N 2/02 (2006.01); H04R 25/00 (2006.01)
CPC A61N 1/0456 (2013.01) [A61N 1/36014 (2013.01); A61N 1/36021 (2013.01); A61N 1/36034 (2017.08); A61N 1/36053 (2013.01); A61N 1/40 (2013.01); A61N 2/008 (2013.01); A61N 2/02 (2013.01); H04R 25/305 (2013.01); H04R 25/505 (2013.01); H04R 25/70 (2013.01); A61N 1/36075 (2013.01); A61N 2/006 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A device for treating a medical condition in a patient, the device comprising:
one or more electrodes having a contact surface configured for contacting an outer skin surface of a patient; and
a power source coupled to the electrodes, wherein the power source is configured to generate one or more electrical impulses and to transmit the electrical impulses to the electrodes and transcutaneously through the outer skin surface of the patient at or near a vagus nerve, wherein the one or more electrical impulses comprises one or more electrical impulses, wherein the one or more electrical pulses comprise bursts of 2 to 20 pulses within each burst, wherein each burst has a frequency of about 5 Hz to about 100 Hz, wherein the one or more electrical impulses is sufficient to modulate the vagus nerve and to stimulate one or more dopamine-producing neurons in the brain of the patient.