US 12,070,582 B2
Drug delivery system with flexible piston assembly
Mehran Mojarrad, Thousand Oaks, CA (US); Ali Nekouzadeh, Simi Valley, CA (US); Susan McConnell Montalvo, Thousand Oaks, CA (US); Scott R. Gibson, Granada Hills, CA (US); Sheldon B. Moberg, Thousand Oaks, CA (US); Joshua Tamsky, Los Angeles, CA (US); and Paul D. Faucher, Escondido, CA (US)
Assigned to AMGEN INC., Thousand Oaks, CA (US)
Filed by AMGEN INC., Thousand Oaks, CA (US)
Filed on Nov. 10, 2020, as Appl. No. 17/094,176.
Claims priority of provisional application 62/949,356, filed on Dec. 17, 2019.
Claims priority of provisional application 62/937,149, filed on Nov. 18, 2019.
Prior Publication US 2021/0146055 A1, May 20, 2021
Int. Cl. A61M 5/315 (2006.01)
CPC A61M 5/31513 (2013.01) [A61M 2005/3152 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A gas-driven drug delivery device comprising:
a drug container having a drug outlet and configured to contain a drug;
a plunger slidably coupled with the drug container;
a gas chamber configured to contain a pressurized gas; and
a piston assembly including:
a flexible pushrod workingly coupled with the plunger,
a non-linear guide including a non-linear guide pathway at least partially surrounding the flexible pushrod,
a cylinder having a gas inlet and a bore at least partially surrounding the flexible pushrod, the gas inlet configured to be at least selectively in fluid communication with the gas chamber, and
a piston in operable communication with the flexible pushrod and movable within the bore of the cylinder in response to the pressurized gas entering the cylinder through the gas inlet.