US 12,070,488 B2
Methods of treating Kawasaki disease
Michael A. Portman, Seattle, WA (US)
Assigned to Seattle Children's Hospital, Seattle, WA (US)
Filed by Seattle Children's Hospital, Seattle, WA (US)
Filed on Jan. 18, 2022, as Appl. No. 17/648,242.
Application 17/648,242 is a continuation of application No. 16/401,698, filed on May 2, 2019, granted, now 11,253,569.
Claims priority of provisional application 62/666,316, filed on May 3, 2018.
Prior Publication US 2022/0339244 A1, Oct. 27, 2022
Int. Cl. A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61K 31/047 (2006.01); A61K 31/05 (2006.01); A61K 31/192 (2006.01); A61K 31/25 (2006.01); A61K 31/60 (2006.01); A61K 31/7016 (2006.01); A61K 31/717 (2006.01); A61K 31/718 (2006.01); A61K 39/395 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01); A61K 47/36 (2006.01); A61P 17/00 (2006.01); C07K 16/06 (2006.01); C07K 16/24 (2006.01)
CPC A61K 38/1709 (2013.01) [A61K 9/0019 (2013.01); A61K 31/047 (2013.01); A61K 31/05 (2013.01); A61K 31/192 (2013.01); A61K 31/25 (2013.01); A61K 31/60 (2013.01); A61K 31/7016 (2013.01); A61K 31/717 (2013.01); A61K 31/718 (2013.01); A61K 39/395 (2013.01); A61K 39/39516 (2013.01); A61K 39/3955 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/183 (2013.01); A61K 47/36 (2013.01); A61P 17/00 (2018.01); C07K 16/06 (2013.01); C07K 16/241 (2013.01)] 20 Claims
 
1. A method of treating acute Kawasaki Disease (KD) in a human subject in need thereof, the method comprising:
administering only to the subject that is aged 12 months or older:
a therapeutically effective amount of intravenous gamma globulin (IVIG), and
a therapeutically effective amount of etanercept.