US 12,070,479 B1
Decarboxylated cannabis compositions and methods of making the same
Alexander John Levine, Studio City, CA (US); and David Spiegel, Hamden, CT (US)
Assigned to PT WORLDWIDE, Studio City, CA (US)
Filed by PT Worldwide, Studio City, CA (US)
Filed on Apr. 19, 2022, as Appl. No. 17/659,736.
Claims priority of provisional application 63/176,560, filed on Apr. 19, 2021.
Int. Cl. A61K 31/352 (2006.01); A61K 31/05 (2006.01); A61K 36/185 (2006.01); B01D 5/00 (2006.01); B01J 6/00 (2006.01)
CPC A61K 36/185 (2013.01) [A61K 31/05 (2013.01); A61K 31/352 (2013.01); B01D 5/006 (2013.01); B01J 6/008 (2013.01)] 20 Claims
 
1. A method for preparing a decarboxylated cannabis composition, comprising:
(a) adding cannabis material to a reaction chamber,
(b) treating the reaction chamber with inert gas,
(c) sealing the reaction chamber,
(d) initiating a decarboxylation reaction of the cannabis material at about 70° C. to about 150° C., for about 0.5 hour to about 10 hours in the sealed reaction chamber,
(e) condensing within the sealed reaction chamber at about 0° C. to about 20° C.,
(f) retaining a decarboxylated cannabis composition within the sealed reaction chamber,
(g) optionally, storing the sealed reaction chamber comprising the decarboxylated cannabis composition at a temperature of about −40° C. to about −20° C., and
(h) unsealing the sealed reaction chamber to form an unsealed reaction chamber comprising the decarboxylated cannabis composition,
wherein no or substantially no solvent is added to the reaction chamber, and
wherein no by-products are removed from the reaction chamber prior to the unsealing of the sealed reaction chamber.