	US 12,070,468 B2
	Compositions and methods for the treatment and prevention of vascular malformations
Carrie J. Shawber, Washington, NJ (US); June K. Wu, New York, NY (US); and Ajit Muley, San Mateo, CA (US)
Assigned to The Trustees of Columbia University in the City of New York, New York, NY (US)
Filed by The Trustees of Columbia University in the City of New York, New York, NY (US)
Filed on Nov. 10, 2022, as Appl. No. 17/984,734.
Application 17/984,734 is a continuation of application No. PCT/US2021/032374, filed on May 14, 2021.
Claims priority of provisional application 63/024,670, filed on May 14, 2020.
Prior Publication US 2023/0141664 A1, May 11, 2023
Int. Cl. A61K 31/145 (2006.01); A61K 31/407 (2006.01); A61K 31/501 (2006.01); A61K 31/69 (2006.01); A61K 38/06 (2006.01); A61K 38/07 (2006.01); A61P 9/14 (2006.01)

CPC A61K 31/69 (2013.01) [A61K 31/145 (2013.01); A61K 31/407 (2013.01); A61K 31/501 (2013.01); A61K 38/06 (2013.01); A61K 38/07 (2013.01); A61P 9/14 (2018.01)]

6 Claims

1. A method of treating a vascular malformation in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of disulfiram, wherein the vascular malformation is chosen from the group consisting of lymphatic, venous, capillary, and combinations thereof.