US 12,070,304 B2
System and method for diagnosis, monitoring, and treatment of obstructive sleep apnea
Amal Isaiah, Hanover, MD (US); Jeffrey S. Wolf, Owings Mills, MD (US); and Stephen Restaino, Columbia, MD (US)
Assigned to University Of Maryland, Baltimore, Baltimore, MD (US); and Sonosa Medical, Inc., Baltimore, MD (US)
Appl. No. 16/964,736
Filed by University Of Maryland, Baltimore, Baltimore, MD (US); and Sonosa Medical, Inc., Baltimore, MD (US)
PCT Filed Jan. 24, 2019, PCT No. PCT/US2019/014931
§ 371(c)(1), (2) Date Jul. 24, 2020,
PCT Pub. No. WO2019/147793, PCT Pub. Date Aug. 1, 2019.
Claims priority of provisional application 62/621,094, filed on Jan. 24, 2018.
Prior Publication US 2020/0345267 A1, Nov. 5, 2020
Int. Cl. A61B 5/08 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61N 7/00 (2006.01)
CPC A61B 5/0826 (2013.01) [A61B 5/14542 (2013.01); A61B 5/4818 (2013.01); A61B 5/4836 (2013.01); A61B 5/6822 (2013.01); A61B 5/7405 (2013.01); A61B 5/742 (2013.01); A61B 5/7455 (2013.01); A61N 7/00 (2013.01); A61N 2007/0026 (2013.01); A61N 2007/0052 (2013.01); A61N 2007/0073 (2013.01)] 28 Claims
OG exemplary drawing
 
1. A system comprising:
an organ stimulating transducer configured for placement adjacent to an organ of a subject, with the placement of the organ stimulating transducer being external the subject, and with the organ stimulating transducer configured to identify a location of the organ to be stimulated via a location of Ranine veins of the subject;
a first sensor for detecting a hypoxic condition in the subject;
at least one processor; and
at least one memory including one or more sequences of instructions, the at least one memory and the one or more sequences of instructions configured to, with the at least one processor, cause the system to perform at least the following,
receive a first signal from the first sensor,
determine whether the subject is in the hypoxic condition during an obstruction of an airway of the subject based at least in part on the first signal received from the first sensor,
when it is determined that the subject is in the hypoxic condition during the obstruction of the airway of the subject, send an output signal to the organ stimulating transducer, wherein the output signal is configured to cause the organ stimulating transducer to stimulate the organ of the subject based on the identified location.