US 12,070,031 B2
Compositions and methods for systemic delivery of cargos in vascular plants
Tyler Maxwell, Winter Haven, FL (US); Swadeshmukul Santra, Winter Park, FL (US); and Parthiban Rajasekaran, Orlando, FL (US)
Assigned to UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC., Orlando, FL (US)
Filed by UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC., Orlando, FL (US)
Filed on Sep. 17, 2020, as Appl. No. 17/024,195.
Prior Publication US 2022/0079147 A1, Mar. 17, 2022
Int. Cl. A01N 25/26 (2006.01); A01N 43/16 (2006.01)
CPC A01N 25/26 (2013.01) [A01N 43/16 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A composition for systemic delivery of at least one cargo in a vascular plant, the composition comprising:
at least one cargo delivery particle,
wherein the at least one cargo delivery particle comprises a core and a shell; the at least one cargo delivery particle having a size of less than about 10 nanometers,
the core comprising at least one nanostructure, the nanostructure comprising ZnS doped with Manganese, wherein the core comprises about 1 to about 5%, by weight, zinc; and wherein the cargo delivery particle is produced by mixing a zinc-manganese solution with a NAC-sulfide solution, and wherein a ratio of Zn to NAC in the composition is from about 1:1 to about 1:0.25,
wherein the shell comprises a coating material; wherein the coating material comprises N-acetylcysteine (NAC);
wherein the core further comprises at least one additional metal micronutrient wherein the additional metal micronutrient comprises iron, and
at least one cargo disposed on the shell of the cargo delivery particle, wherein the at least one cargo comprises a positively charged agricultural antibiotic, and wherein the at least one cargo delivery particle is free of cadmium and lead.