CPC C07D 413/14 (2013.01) [A61P 17/00 (2018.01); C07D 333/24 (2013.01); C07D 409/06 (2013.01); C07D 409/12 (2013.01); C07D 413/06 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01)] | 13 Claims |
1. A compound of Formula I represented by
wherein
R1, R2, R3, R4, R5 are each independently selected from hydrogen, halogen, phenyl, straight chain or branched C1-C5 alkyl, straight chain or branched C2-C5 alkenyl, straight chain or branched C1-C5 alkoxyalkyl, straight chain or branched C1-C5 alkoxyaryl, aryl, CF3, C3-C7 aromatic or aliphatic heterocycle comprising at least one hetero atom selected from a group of O, N and S; or
any of two adjacent R groups R1, R2, R3, R4, and R5 may together form (1) a naphthalene; or (2) a 5-6 membered aromatic or aliphatic ring comprising at least one hetero atom selected from a group of O, N and S;
Ra and Rb are each independently selected from hydrogen, straight chain or branched C1-C5 alkyl, straight chain or branched C1-C5 aralkyl, straight chain or branched C2-C5 alkenyl, straight chain or branched C2-C5 alkynyl, or both Ra, and Rb together form a 3-7 membered ring comprising at least one hetero atom selected from a group of O, N and S;
R6 and R7 are each independently selected from hydrogen, unsubstituted straight chain or branched C1-C5 alkyl, straight chain or branched C1-C5 aralkyl, straight chain or branched C2-C5 alkenyl, straight chain or branched C2-C5 alkynyl; or
—CH2(CH2)nNRcRd wherein n is 0-3, and Rc and Rd are both CH3 or together form a 3-7 membered aromatic or aliphatic heterocycle comprising at least one hetero atom selected from a group of O, N and S; or
both R6 and R7 may together form a 3-7 membered aliphatic heterocycle comprising at least one hetero atom selected from O, N and S;
provided that R6 and R7 are not both hydrogen;
or a stereoisomer; a racemic mixture; a geometrical isomer; a tautomer; a pharmaceutically acceptable salt, hydrate, or solvate; a solid form; or a mixture of solid forms thereof.
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