CPC C07C 213/10 (2013.01) [C07C 213/02 (2013.01); C07D 301/03 (2013.01); C07C 2601/14 (2017.05)] | 20 Claims |
1. A method of purifying a terpenoid amino alcohol derivative represented by formula V′, comprising:
providing a crude terpenoid amino alcohol derivative represented by formula V′ below:
performing an acid/base crystallization process of the crude terpenoid amino alcohol derivative represented by formula V′ to obtain an organic salt represented by formula V″ below:
and
reacting the organic salt represented by formula V″ with at least one solvent selected from NaOH, toluene, cyclopentyl methyl ether, diethyl ether, and dimethoxyethane to obtain a purified terpenoid amino alcohol derivative represented by formula V′,
wherein R, R1, and R2 are independently a substituted or unsubstituted C1-C6 alkyl.
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