	US 11,738,081 B2
	Polynucleotides encoding IL33 antibodies and methods of using the same
Emma S. Cohen, Cambridge (GB); David C. Lowe, Cambridge (GB); Robin Butler, Cambridge (GB); Ian C. Scott, Cambridge (GB); Katherine A. Vousden, Cambridge (GB); Martin D. Strain, Cambridge (GB); Sara Carmen, Cambridge (GB); Elizabeth H. England, Cambridge (GB); Benjamin P. Kemp, Cambridge (GB); David G. Rees, Cambridge (GB); Catherine L. Overed-Sayer, Cambridge (GB); Tomas M. Mustelin, Gaithersburg, MD (US); Matthew Sleeman, Cambridge (GB); and Kirsty Houslay, Cambridge (GB)
Assigned to MEDIMMUNE LIMITED, Cambridge (GB)
Filed by MEDIMMUNE LIMITED, Cambridge (GB)
Filed on Apr. 10, 2020, as Appl. No. 16/845,121.
Application 16/845,121 is a division of application No. 15/562,228, granted, now 10,668,150, previously published as PCT/EP2016/056973, filed on Mar. 30, 2016.
Claims priority of provisional application 62/140,913, filed on Mar. 31, 2015.
Prior Publication US 2020/0353078 A1, Nov. 12, 2020
Int. Cl. A61K 39/395 (2006.01); C07K 16/24 (2006.01); A01K 67/027 (2006.01); C07K 14/54 (2006.01); A61P 11/06 (2006.01); A61K 39/00 (2006.01)

CPC A61K 39/3955 (2013.01) [A01K 67/0278 (2013.01); A61P 11/06 (2018.01); C07K 14/54 (2013.01); C07K 16/244 (2013.01); A01K 2217/072 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01)]

15 Claims

1. A polynucleotide encoding an antibody or antigen binding fragment thereof which specifically binds to IL-33, wherein the antibody or antigen binding fragment thereof comprises a variable heavy domain (VH) comprising a VHCDR1 having the sequence of SEQ ID NO: 543, a VHCDR2 having the sequence of SEQ ID NO: 544, and a VHCDR3 having the sequence of SEQ ID NO: 545, and a variable light domain (VL) comprising a VLCDR1 having the sequence of SEQ ID NO: 548, a VLCDR2 having the sequence of SEQ ID NO: 549, and a VLCDR3 having the sequence of SEQ ID NO: 550.