CPC A61K 31/4725 (2013.01) [A61K 38/21 (2013.01); C07D 455/03 (2013.01); C07D 491/147 (2013.01); C07D 495/14 (2013.01)] | 15 Claims |
1. A compound represented by Formula (I):
or a pharmaceutically acceptable salt thereof, wherein:
R1 is hydrogen or halo;
R2 is hydrogen;
R3 is hydrogen, halo, optionally substituted C3-C12 cycloalkyl, optionally substituted C3-C12 cycloalkenyl, optionally substituted 3- to 12-membered heterocyclic, optionally substituted aryl, or optionally substituted heteroaryl;
A is optionally substituted 5-membered heteroaryl;
R4 is hydrogen;
R5 is hydrogen;
R6 is optionally substituted C1-C6 alkyl;
R7 is hydrogen;
R8 is hydrogen; and
W is —COOH.
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