US 11,737,701 B2
Methods, systems and media for reconstructing bioelectronic lead placement
Alexander David Wissner-Gross, Cambridge, MA (US); Suraj Kapa, Rochester, MN (US); James Y. Lee, Stamford, CT (US); Desmond B. Keenan, Stevenson Ranch, CA (US); Natalia Drapeau, Geneva (CH); and Kenneth L. Londoner, Westport, CT (US)
Assigned to BioSig Technologies, Inc., Westport, CT (US)
Filed by BioSig Technologies, Inc., Westport, CT (US)
Filed on Apr. 26, 2021, as Appl. No. 17/240,809.
Claims priority of provisional application 63/018,307, filed on Apr. 30, 2020.
Prior Publication US 2021/0345933 A1, Nov. 11, 2021
Int. Cl. A61B 5/00 (2006.01); A61B 5/349 (2021.01); A61B 5/389 (2021.01); A61B 5/327 (2021.01)
CPC A61B 5/349 (2021.01) [A61B 5/327 (2021.01); A61B 5/389 (2021.01)] 30 Claims
OG exemplary drawing
 
1. A system for reconstructing bioelectronic lead placement, comprising:
a processor configured to:
receive electrophysiology (EP) signals from a plurality of electrodes, the plurality of electrodes having been positioned on a patient's body for collection of the EP signals;
determine biological signaling time latencies between the EP signals from one or more pairs of the plurality of electrodes over one or more sampling time periods;
generate a weighted graph of the plurality of electrodes based on the biological signaling time latencies;
determine, based on the weighted graph and known positions, scales, or orientations of electrodes, that one or more of the plurality of electrodes on the patient are misplaced so as to yield an incorrect reading; and
correct a misplacement of the plurality of electrodes based on the determination that the one or more of the plurality of electrodes on the patient are misplaced.