US 11,737,458 B2
Fibrous substrate for capture of gram negative bacteria
David W. Koenig, Menasha, WI (US); Amy L. Vanden Heuvel, Hortonville, WI (US); Vinod Chaudhary, Appleton, WI (US); Scott W. Wenzel, Neenah, WI (US); Divesh Bhatt, Marietta, GA (US); and Kathleen Engelbrecht, Kaukauna, WI (US)
Assigned to Kimberly-Clark Worldwide, Inc., Neenah, WI (US)
Appl. No. 15/561,311
Filed by Kimberly-Clark Worldwide, Inc., Neenah, WI (US)
PCT Filed Apr. 1, 2015, PCT No. PCT/US2015/023813
§ 371(c)(1), (2) Date Sep. 25, 2017,
PCT Pub. No. WO2016/160006, PCT Pub. Date Oct. 6, 2016.
Prior Publication US 2018/0098536 A1, Apr. 12, 2018
Int. Cl. A01N 25/34 (2006.01); A61K 31/717 (2006.01); A61K 31/74 (2006.01); D21J 1/16 (2006.01); A61K 9/70 (2006.01)
CPC A01N 25/34 (2013.01) [A61K 31/717 (2013.01); A61K 31/74 (2013.01); D21J 1/16 (2013.01); A61K 9/70 (2013.01)] 19 Claims
 
1. A method for removing Gram negative bacteria from a surface, the method comprising placing a fibrous substrate in contact with Gram negative bacteria present on the surface, wherein the fibrous substrate comprises absorbent pulp fibers, synthetic thermoplastic fibers and a capturing agent formulation comprising a capturing agent and a carrier, wherein the capturing agent comprises a nonionic amine-functionalized silicone polymer having hydrophilic and lipophilic regions, wherein the capturing agent is incorporated into the fibrous substrate during formation or coated onto all or a portion of a surface of the fibrous substrate, and is present in or on the fibrous substrate in an amount effective to result in an increase of Gram negative bacteria present on the fibrous substrate of at least about 1 log;
wherein the nonionic amine-functionalized silicone polymer having hydrophilic and lipophilic regions is polymethyl(3-aminopropyl)-siloxane or polymethyl[3-(2-aminoethyl)aminopropyl]-siloxane;
wherein the fibrous substrate is a wipe;
wherein the capturing agent is free of an acrylic acid polymer; and
wherein the capturing agent formulation is free from water and alcohol.