US 12,066,413 B2
Chromatography column and method of assembling the same
Daniel Salomonsson, Uppsala (SE); and Mats Lundkvist, Uppsala (SE)
Assigned to Cytiva Sweden AB, Uppsala (SE)
Appl. No. 17/294,710
Filed by Cytiva Sweden AB, Uppsala (SE)
PCT Filed Dec. 4, 2019, PCT No. PCT/EP2019/083735
§ 371(c)(1), (2) Date May 18, 2021,
PCT Pub. No. WO2020/115165, PCT Pub. Date Jun. 11, 2020.
Claims priority of application No. 1819984 (GB), filed on Dec. 7, 2018.
Prior Publication US 2022/0018817 A1, Jan. 20, 2022
Int. Cl. G01N 30/60 (2006.01); B01D 15/20 (2006.01); B01D 15/22 (2006.01)
CPC G01N 30/6082 (2013.01) [B01D 15/206 (2013.01); B01D 15/22 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A chromatographic separation column assembly comprising:
a column cylinder having a cylinder wall including an inner wall surface partially defining a column volume, and
a first column component comprising an adapter plate having a sliding seal disposed therearound and a second column component comprising a base, wherein both the first column component and the second column component are insertable into to the column cylinder,
wherein at least an adapter plate edge region and a base edge region of the are intended to be in contact or adjacent a part of the inner wall surface in use, the adapter plate and base edge regions and the contacting or adjacent part of the inner wall surface each being formed from a compatible heat fusible material or materials, and
wherein at least the cylinder wall in the area of the contacting or adjacent part of the inner wall surface is formed from a material which allows transmission of light energy needed to cause said fusing of the adapter plate edge region and the base edge region to the inner wall surface.