US 12,065,650 B2
Heterologous biosynthesis of nodulisporic acid
Matthew Joseph Nicholson, Canterbury (NZ); Sarah Adeline Kessans, Christchurch (NZ); Emily Jane Parker, Wellington (NZ); Leyla Yolanda Bustamante Rodriguez, Prebbleton (NZ); David Barry Scott, Palmerston North (NZ); Kyle Cornelius Van de Bittner, Wellington (NZ); and Craig John Van Dolleweerd, Prebbleton (NZ)
Assigned to Massey University, Palmerston (NZ)
Filed by VICTORIA LINK LIMITED, Wellington (NZ)
Filed on Aug. 1, 2022, as Appl. No. 17/816,630.
Application 17/816,630 is a division of application No. 16/651,065, granted, now 11,453,882, previously published as PCT/IB2018/057528, filed on Sep. 28, 2018.
Claims priority of application No. 2017903956 (AU), filed on Sep. 29, 2017.
Prior Publication US 2023/0365976 A1, Nov. 16, 2023
Int. Cl. C12N 15/52 (2006.01); A01N 63/30 (2020.01); A01N 63/50 (2020.01); C12N 15/80 (2006.01); C12P 17/18 (2006.01)
CPC C12N 15/52 (2013.01) [A01N 63/30 (2020.01); A01N 63/50 (2020.01); C12N 15/80 (2013.01); C12P 17/18 (2013.01)] 13 Claims
 
1. An isolated polynucleotide comprising at least 70% nucleic acid sequence identity to the nucleic acid sequence of SEQ ID NO: 5 or 20 wherein the polynucleotide encodes a polypeptide of SEQ ID NO: 6 or SEQ ID NO: 21 respectively, and wherein each polypeptide has P450 oxygenase activity.