US 12,065,511 B2
Aromatic-cationic peptides and uses of same
D. Travis Wilson, Newton, MA (US); Marc W. Andersen, Raleigh, NC (US); and Elizabeth Mead, Hertfordshire (GB)
Assigned to STEALTH BIOTHERAPEUTICS INC., Needham, MA (US)
Filed by STEALTH BIOTHERAPEUTICS INC., Needham, MA (US)
Filed on Mar. 13, 2020, as Appl. No. 16/818,560.
Application 16/818,560 is a continuation of application No. 15/865,434, filed on Jan. 9, 2018, abandoned.
Application 15/865,434 is a continuation of application No. 14/363,035, filed on Jun. 5, 2014.
Application 14/363,035 is a continuation of application No. PCT/US2012/067984, filed on Dec. 5, 2012.
Claims priority of provisional application 61/569,120, filed on Dec. 9, 2011.
Prior Publication US 2021/0040149 A1, Feb. 11, 2021
Int. Cl. C07K 5/10 (2006.01); A61K 38/06 (2006.01); A61K 38/07 (2006.01); C07C 229/26 (2006.01); C07D 209/16 (2006.01); C07K 5/06 (2006.01); C07K 5/065 (2006.01); C07K 5/068 (2006.01); C07K 5/072 (2006.01); C07K 5/08 (2006.01); C07K 5/087 (2006.01); C07K 5/09 (2006.01); C07K 5/107 (2006.01); C07K 5/11 (2006.01); G01N 33/68 (2006.01)
CPC C07K 5/10 (2013.01) [A61K 38/06 (2013.01); A61K 38/07 (2013.01); C07C 229/26 (2013.01); C07D 209/16 (2013.01); C07K 5/06 (2013.01); C07K 5/06078 (2013.01); C07K 5/06086 (2013.01); C07K 5/06095 (2013.01); C07K 5/08 (2013.01); C07K 5/0812 (2013.01); C07K 5/0815 (2013.01); C07K 5/0817 (2013.01); C07K 5/1016 (2013.01); C07K 5/1019 (2013.01); G01N 33/68 (2013.01)] 6 Claims
 
1. An aromatic-cationic peptide consisting of the amino acid sequence D-Arg-4-methoxy-2,6-dimethyltyrosine-Lys-Phe-NH2, or a pharmaceutically acceptable salt thereof.