US 12,065,490 B2
Chimeric antigen receptors and methods of making
Laurence J. N. Cooper, Houston, TX (US); Ana Beatriz Korngold, Houston, TX (US); Brian A. Rabinovich, Houston, TX (US); Harjeet Singh, Houston, TX (US); and Simon Olivares, Houston, TX (US)
Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed by BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed on Feb. 26, 2021, as Appl. No. 17/187,074.
Application 17/187,074 is a continuation of application No. 16/145,790, filed on Sep. 28, 2018, abandoned.
Application 16/145,790 is a continuation of application No. 15/118,245, granted, now 10,125,193, issued on Nov. 13, 2018, previously published as PCT/US2015/016057, filed on Feb. 16, 2015.
Claims priority of provisional application 61/940,339, filed on Feb. 14, 2014.
Prior Publication US 2021/0324071 A1, Oct. 21, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/725 (2006.01); A61K 35/17 (2015.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 9/12 (2006.01); C12N 15/85 (2006.01); A61K 35/12 (2015.01)
CPC C07K 16/2803 (2013.01) [A61K 35/17 (2013.01); C07K 14/4746 (2013.01); C07K 14/4748 (2013.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C12N 9/1241 (2013.01); C12N 15/85 (2013.01); C12Y 207/07 (2013.01); A61K 2035/124 (2013.01); C07K 2317/622 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01)] 20 Claims
 
1. A polypeptide encoded by a nucleic acid sequence comprising nucleotides 67-1485 of SEQ ID NO: 5.