US 12,065,485 B2
Treatment of staphylococcal disorders
Gabriel Nunez, Ann Arbor, MI (US); Jon Oscherwitz, Ann Arbor, MI (US); Kemp Cease, Ann Arbor, MI (US); Yumi Nakamura, Ann Arbor, MI (US); and Tyler Nygaard, Bozeman, MT (US)
Assigned to THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US)
Filed by THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US)
Filed on Oct. 22, 2021, as Appl. No. 17/508,692.
Application 17/508,692 is a continuation of application No. 14/774,589, granted, now 11,198,724, previously published as PCT/US2014/029768, filed on Mar. 14, 2014.
Claims priority of provisional application 61/784,476, filed on Mar. 14, 2013.
Prior Publication US 2022/0048979 A1, Feb. 17, 2022
Int. Cl. C07K 16/12 (2006.01); A61K 31/05 (2006.01); A61K 31/18 (2006.01); A61K 31/192 (2006.01); A61K 31/196 (2006.01); A61K 31/235 (2006.01); A61K 31/277 (2006.01); A61K 31/366 (2006.01); A61K 31/37 (2006.01); A61K 31/47 (2006.01); A61K 31/713 (2006.01); A61K 39/00 (2006.01); A61K 39/085 (2006.01); A61K 39/40 (2006.01); A61K 45/06 (2006.01); C12N 15/113 (2010.01)
CPC C07K 16/1271 (2013.01) [A61K 31/05 (2013.01); A61K 31/18 (2013.01); A61K 31/192 (2013.01); A61K 31/196 (2013.01); A61K 31/235 (2013.01); A61K 31/277 (2013.01); A61K 31/366 (2013.01); A61K 31/37 (2013.01); A61K 31/47 (2013.01); A61K 31/713 (2013.01); A61K 39/085 (2013.01); A61K 39/40 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01); A61K 2039/505 (2013.01); A61K 2039/575 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01)] 3 Claims
OG exemplary drawing
 
1. A method for inhibiting Staphylococcus aureus agr virulence comprising the step of administering an effective amount of carnosic acid to an individual to inhibit the Staphylococcus aureus agr virulence in the individual with minimal reduction in Staphylococcus aureus growth.