CPC C07D 401/14 (2013.01) | 20 Claims |
1. A compound according to formula (I)
wherein X is fluoro or chloro;
R1 is selected from
wherein R5 is independently selected from (C1-C4)alkyl, (C3-C4)cycloalkyl, and —CH2—(C3-C4)cycloalkyl, wherein said (C1-C4)alkyl, (C3-C4)cycloalkyl, and —CH2—(C3-C4)cycloalkyl are optionally substituted with substituents independently selected from one hydroxy group and 1, 2, or 3 fluoro;
R2 is selected from hydrogen, (C1-C3)alkyl, cyclopropyl, and chloro, wherein said (C1-C3)alkyl is optionally substituted with one or more fluoro;
R3 is selected from hydrogen, (C1-C3)alkyl, cyclopropyl, and chloro, wherein said (C1-C3)alkyl is optionally substituted with one or more fluoro; and
R4 is selected from hydrogen, (C1-C3)alkyl, cyclopropyl, (C1-C2)alkoxy, cyano, methylsulfone, fluoro, and chloro; wherein said (C1-C3)alkyl and (C1-C2)alkoxy are optionally substituted with one or more fluoro;
provided that at least one of R2 and R3 is not hydrogen;
or pharmaceutically acceptable salts thereof.
|