US 12,064,763 B2
Systems and methods for determining presence and/or characteristics of target analytes in a sample
Alex Dehgan, Washington, WA (US); Paul Bunje, Los Angeles, CA (US); Hallie Holmes, Seattle, WA (US); David Baisch, Seattle, WA (US); Cifeng Fang, Redmond, WA (US); Gareth Fotouhi, Seattle, WA (US); Misa Winters, Brier, WA (US); Sam Kelly, Arlington, VI (US); and Brad Zamft, New York, NY (US)
Assigned to Conservation X Labs, Inc
Appl. No. 17/770,643
Filed by Conservation X Labs, Inc, Northwest, WA (US)
PCT Filed Oct. 21, 2020, PCT No. PCT/US2020/056727
§ 371(c)(1), (2) Date Apr. 21, 2022,
PCT Pub. No. WO2021/081136, PCT Pub. Date Apr. 29, 2021.
Claims priority of provisional application 62/923,637, filed on Oct. 21, 2019.
Prior Publication US 2022/0347682 A1, Nov. 3, 2022
Int. Cl. B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 21/03 (2006.01); G01N 21/25 (2006.01); G01N 33/53 (2006.01); G01N 35/00 (2006.01)
CPC B01L 3/502715 (2013.01) [B01L 3/5085 (2013.01); B01L 7/52 (2013.01); G01N 21/0332 (2013.01); G01N 21/253 (2013.01); G01N 33/53 (2013.01); B01L 2200/0684 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); G01N 2035/00376 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A cartridge for providing a target analyte for detection, said cartridge comprising:
a base portion including:
a receiving area located at a center region of said base portion, wherein said base portion has a circular shape;
multiple reaction wells radially disposed near a perimeter of said base portion, wherein said receiving area is a surface that is raised relative to said multiple reaction wells; and
multiple connecting tracks that substantially linearly extend from a region at or proximate to said receiving area to said multiple reaction wells and designed to convey a sample including said target analyte from said receiving area to said multiple reaction wells, such that one end of each of said connecting tracks is fluidly connected to said receiving area and another end of each of said connecting tracks is fluidly connected to each of said multiple reaction wells; and
a cap portion including:
an inlet port located at a center cap region of said cap portion;
multiple reaction well covers radially disposed near a perimeter of said cap portion;
multiple connecting track covers that extend from said inlet port to said multiple reaction well covers;
multiple vents designed to regulate flow of said sample into said multiple reaction wells;
wherein said cap portion has a circular shape; and
wherein in an assembled state of said cartridge, said inlet port covers said receiving area, said multiple reaction well covers cover said multiple reaction wells, and said multiple connecting track covers cover said multiple connecting tracks to define an enclosed fluid flow path for said sample.