US 12,064,758 B2
Stabilized reagent compositions, systems and methods using the same
Dorian Cauceglia, Fort Myers, FL (US)
Assigned to WATTS REGULATOR CO., North Andover, MA (US)
Filed by Watts Regulator Co., North Andover, MA (US)
Filed on Aug. 20, 2021, as Appl. No. 17/407,306.
Prior Publication US 2023/0058190 A1, Feb. 23, 2023
Int. Cl. B01L 3/00 (2006.01); B01D 15/36 (2006.01); G01N 21/78 (2006.01); G01N 33/18 (2006.01)
CPC B01L 3/502 (2013.01) [B01D 15/363 (2013.01); B01L 3/523 (2013.01); B01L 3/567 (2013.01); G01N 21/78 (2013.01); G01N 33/18 (2013.01); B01L 2200/16 (2013.01); B01L 2300/069 (2013.01); B01L 2300/12 (2013.01); B01L 2400/0605 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A fluid content monitoring system, comprising:
a reagent store comprising a stabilized indicator composition, the stabilized indicator composition comprising a solvent, a stabilizer, and an indicator, the indicator configured to indicate an amount of one or more constituents in a fluid sample;
a pump assembly fluidly coupled to a sample source and the reagent store;
a sample analyzer fluidly coupled to the pump assembly; and
a stabilizer removal system fluidly coupled to the reagent store and the sample analyzer; wherein:
the pump assembly is configured to cause said stabilized indicator composition to flow through said stabilizer removal system, thereby causing the stabilizer removal system to remove the stabilizer from the stabilized indicator composition and produce a fluid stream comprising said solvent and said indicator;
said pump assembly is further configured to convey said fluid stream and a fluid from said sample source to a chamber in said sample analyzer to form a test sample; and
said sample analyzer is configured to analyze the test sample to determine an amount of at least one constituent in said test sample;
wherein:
said reagent store comprises a reagent container; and
at least a portion of said stabilizer removal system is disposed within said reagent container.
 
13. A fluid content monitoring system, comprising:
a reagent store comprising a stabilized indicator composition, the stabilized indicator composition comprising a solvent, a stabilizer, and an indicator, the indicator configured to indicate an amount of one or more constituents in a fluid sample;
a pump assembly fluidly coupled to a sample source and the reagent store;
a sample analyzer fluidly coupled to the pump assembly; and
a stabilizer removal system fluidly coupled to the reagent store and the sample analyzer, the stabilizer removal system comprising an ion exchange column comprising an ion exchange resin; wherein:
the pump assembly is configured to cause said stabilized indicator composition to flow through said stabilizer removal system, thereby causing the stabilizer removal system to remove the stabilizer from the stabilized indicator composition and produce a fluid stream comprising said solvent and said indicator;
said pump assembly is further configured to convey said fluid stream and a fluid from said sample source to a chamber in said sample analyzer to form a test sample;
said sample analyzer is configured to analyze the test sample to determine an amount of at least one constituent in said test sample; and
a check valve upstream of the ion exchange resin and a filter downstream of the ion exchange resin.