US 12,064,627 B2
Systems and methods for targeted sacral nerve stimulation
Warren Grill, Durham, NC (US); James Hokanson, Durham, NC (US); and Christopher Langdale, Durham, NC (US)
Assigned to DUKE UNIVERSITY, Durham, NC (US)
Filed by DUKE UNIVERSITY, Durham, NC (US)
Filed on May 6, 2021, as Appl. No. 17/313,619.
Claims priority of provisional application 63/021,719, filed on May 8, 2020.
Prior Publication US 2021/0346695 A1, Nov. 11, 2021
Int. Cl. A61N 1/36 (2006.01)
CPC A61N 1/3606 (2013.01) [A61N 1/36007 (2013.01); A61N 1/36135 (2013.01); A61N 1/3615 (2013.01)] 26 Claims
OG exemplary drawing
 
1. A method for determining electrode location for neural stimulation in a subject, the method comprising:
electrically stimulating at least one peripheral nerve and recording electrical activity in at least one target nerve;
electrically stimulating at least one target nerve and recording electrical activity in at least one peripheral nerve; and/or
electrically stimulating at least one target nerve and recording at least one subject perception; and
determining the at least one target nerve having the strongest representation associated with the at least one peripheral nerve and/or the strongest subject perception associated with the at least one peripheral nerve, wherein determining the at least one target nerve having the strongest representation associated with the at least one peripheral nerve comprises determining a sacral nerve side and level in the subject.