	US 12,064,537 B2
	Kits and methods for preparing pathogen-inactivated platelet compositions
Tovo David, San Francisco, CA (US); Betsy Donnelly, Moraga, CA (US); Anna Erickson, Richmond, CA (US); and Naheed Mufti, Danville, CA (US)
Assigned to Cerus Corporation, Concord, CA (US)
Filed by Cerus Corporation, Concord, CA (US)
Filed on Dec. 16, 2021, as Appl. No. 17/553,509.
Application 17/553,509 is a division of application No. 15/910,836, filed on Mar. 2, 2018, granted, now 11,235,090.
Claims priority of provisional application 62/622,127, filed on Jan. 25, 2018.
Claims priority of provisional application 62/467,021, filed on Mar. 3, 2017.
Prior Publication US 2022/0105250 A1, Apr. 7, 2022
Int. Cl. A61M 1/02 (2006.01); A61K 35/19 (2015.01); A61L 2/00 (2006.01); A61M 1/36 (2006.01); A61M 1/34 (2006.01)

CPC A61M 1/0272 (2013.01) [A61K 35/19 (2013.01); A61L 2/0011 (2013.01); A61L 2/0029 (2013.01); A61L 2/0088 (2013.01); A61M 1/0209 (2013.01); A61M 1/3496 (2013.01); A61M 1/3679 (2013.01); A61M 1/3683 (2014.02); A61M 2202/0415 (2013.01); A61M 2202/0427 (2013.01)]

38 Claims

1. A processing set for preparing a pathogen-inactivated platelet composition, comprising:

(a) a first container that contains a pathogen inactivation compound (PIC) and is suitable for combining a platelet composition with the PIC, wherein the PIC is a psoralen;

(b) a second container, coupled to the first container, within which the platelet composition in admixture with the PIC can be photochemically inactivated, wherein the platelet composition has a volume of about 250 mL to about 750 mL; and

(c) a third container containing a compound adsorption device (CAD), wherein the third container is coupled to the second container such that the photochemically inactivated platelet composition can be transferred from the second container to the third container under sterile conditions;

wherein at least one of (i) and (ii) applies:

(i) the volume of the third container is about 1.2 L to about 1.6 L; and

(ii) the surface area of the interior of the third container is about 800 cm²to about 1200 cm².