CPC A61K 51/088 (2013.01) [A61K 51/08 (2013.01); C07B 59/008 (2013.01)] | 9 Claims |
1. A radiolabeled GRPR-antagonist of a formula MC-S-P wherein:
M is a radiometal and C is a metal chelator that binds M,
S is a spacer covalently linked between C and P of formula:
wherein S is covalently attached to the N-terminus of P;
and P is DPhe-Gln-Trp-Ala-Val-Gly-His-NH—CH[CH2—CH(CH3)2]2 (SEQ ID NO: 1);
wherein M is 177Lu.
|