US 12,064,471 B2
Compositions comprising sulforaphane or a sulforaphane precursor and a mushroom extract or powder
Brian Cornblatt, Westminster, MD (US); Grace Cornblatt, Westminster, MD (US); Anton Bzhelyansky, Baltimore, MD (US); and Robert Henderson, Street, MD (US)
Assigned to NUTRAMAX LABORATORIES, INC., Lancaster, SC (US)
Filed by NUTRAMAX LABORATORIES, INC., Lancaster, SC (US)
Filed on Feb. 18, 2021, as Appl. No. 17/178,664.
Application 17/178,664 is a continuation of application No. 14/412,191, granted, now 10,960,057, previously published as PCT/US2013/049248, filed on Jul. 3, 2013.
Claims priority of provisional application 61/794,417, filed on Mar. 15, 2013.
Claims priority of provisional application 61/668,342, filed on Jul. 5, 2012.
Claims priority of provisional application 61/668,386, filed on Jul. 5, 2012.
Claims priority of provisional application 61/668,396, filed on Jul. 5, 2012.
Claims priority of provisional application 61/668,364, filed on Jul. 5, 2012.
Claims priority of provisional application 61/668,374, filed on Jul. 5, 2012.
Claims priority of provisional application 61/668,328, filed on Jul. 5, 2012.
Prior Publication US 2021/0169997 A1, Jun. 10, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A23L 33/105 (2016.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 9/28 (2006.01); A61K 31/19 (2006.01); A61K 31/194 (2006.01); A61K 31/26 (2006.01); A61K 31/357 (2006.01); A61K 31/375 (2006.01); A61K 31/7028 (2006.01); A61K 31/716 (2006.01); A61K 33/06 (2006.01); A61K 36/00 (2006.01); A61K 36/06 (2006.01); A61K 36/07 (2006.01); A61K 36/28 (2006.01); A61K 36/31 (2006.01); A61K 38/47 (2006.01); A61K 45/06 (2006.01); A61K 47/42 (2017.01); A61P 3/06 (2006.01)
CPC A61K 38/47 (2013.01) [A23L 33/105 (2016.08); A61K 9/0053 (2013.01); A61K 9/14 (2013.01); A61K 9/28 (2013.01); A61K 31/19 (2013.01); A61K 31/194 (2013.01); A61K 31/26 (2013.01); A61K 31/357 (2013.01); A61K 31/375 (2013.01); A61K 31/7028 (2013.01); A61K 31/716 (2013.01); A61K 33/06 (2013.01); A61K 36/06 (2013.01); A61K 36/07 (2013.01); A61K 36/28 (2013.01); A61K 36/31 (2013.01); A61K 45/06 (2013.01); A61K 47/42 (2013.01); A61P 3/06 (2018.01); C12Y 302/01147 (2013.01); A23V 2002/00 (2013.01)] 32 Claims
 
1. An orally administrable composition comprising a broccoli extract or powder and one or both of a maitake and a shiitake mushroom extract or powder, the broccoli extract or powder and one or both of a maitake and a shiitake mushroom extract or powder being present in amounts synergistically effective to increase levels or gene expression of NAD(P)H:quinone oxidoreductase 1 (NQO-1).