| CPC A61K 35/74 (2013.01) | 19 Claims |
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1. A method of treating a thermal injury, including:
administering to a subject in need thereof, a therapeutically effective amount of Rhodococcus ruber cell wall skeleton, wherein the Rhodococcus ruber cell wall skeleton is in a form selected from the group consisting of: ointment, cream, emulsion, suspension, paste, gel, lotion, tincture, oil, tablet, aerosol, spray, liniment, powder, dressing, bandage, film, patch and suppository; wherein
the Rhodococcus ruber is the isolated Rhodococcus ruber deposited in CGMCC under Accession No: 17431;
the unit dosage of the Rhodococcus ruber cell wall skeleton is 5 μg to 800 μg;
wherein the Rhodococcus ruber cell wall skeleton is obtained by the following method comprising the following steps:
1) providing a Rhodococcus ruber;
2) disrupting the Rhodococcus ruber to obtain a disrupted product;
3.1) optionally, removing lipids from the disrupted product;
3.2) optionally, removing nucleic acids from the disrupted product;
3.3) optionally, removing proteins from the disrupted product;
3.4) obtaining a product derived from Rhodococcus ruber cell wall;
4) optionally, removing water from the product derived from Rhodococcus ruber cell wall;
5) optionally, performing aliquoting;
wherein, steps 3.1), 3.2) and 3.3) are interchangeable in order or performed in parallel; step 4) and step 5) are interchangeable in order; and
the average particle size of the disruption is 10 nm to 1000 nm.
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