	US 12,064,425 B2
	Compositions and methods for targeting a viral infection
Bing Chen, Boston, MA (US); Gary Frey, Boston, MA (US); and Tianshu Xiao, Boston, MA (US)
Assigned to THE CHILDREN'S MEDICAL CENTER CORPORATION
Appl. No. 17/262,540
Filed by THE CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US)
PCT Filed Jul. 26, 2019, PCT No. PCT/US2019/043612 § 371(c)(1), (2) Date Jan. 22, 2021, PCT Pub. No. WO2020/023849, PCT Pub. Date Jan. 30, 2020.
Claims priority of provisional application 62/711,143, filed on Jul. 27, 2018.
Prior Publication US 2021/0338659 A1, Nov. 4, 2021
Int. Cl. A61K 31/4709 (2006.01)

CPC A61K 31/4709 (2013.01)

8 Claims

1. A method of treating a viral infection, the method comprising:

administering to a subject in need thereof an agent that inhibits the membrane proximal external region (MPER) of a viral envelope (Env), wherein the viral infection is a human immunodeficiency virus-1 (HIV-1) infection or a human immunodeficiency virus-2 (HIV-2) infection, wherein the agent that inhibits MPER is S2C3.