US 12,064,256 B2
Systems and methods for treating cancer and/or augmenting organ function
Landy Toth, Doylestown, PA (US); and Robert S. Schwartz, Inver Grove Heights, MN (US)
Assigned to Autonomix Medical, Inc., Ivyland, PA (US)
Filed by Autonomix Medical, Inc., Ivyland, PA (US)
Filed on Mar. 9, 2022, as Appl. No. 17/690,659.
Application 17/690,659 is a continuation of application No. 16/165,319, filed on Oct. 19, 2018, granted, now 11,272,877.
Application 16/165,319 is a continuation of application No. 14/895,744, granted, now 10,143,419, issued on Dec. 4, 2018, previously published as PCT/US2014/060471, filed on Oct. 14, 2014.
Claims priority of provisional application 62/010,699, filed on Jun. 11, 2014.
Claims priority of provisional application 61/891,242, filed on Oct. 15, 2013.
Prior Publication US 2022/0192595 A1, Jun. 23, 2022
Int. Cl. A61B 5/00 (2006.01); A61B 5/388 (2021.01); A61B 18/14 (2006.01); A61N 1/05 (2006.01); A61N 1/36 (2006.01); A61B 18/00 (2006.01); A61B 18/02 (2006.01); A61B 18/18 (2006.01); A61F 7/12 (2006.01); A61N 7/00 (2006.01); A61N 7/02 (2006.01)
CPC A61B 5/4839 (2013.01) [A61B 5/388 (2021.01); A61B 5/4848 (2013.01); A61B 5/4884 (2013.01); A61B 5/6851 (2013.01); A61B 5/6852 (2013.01); A61B 18/1492 (2013.01); A61N 1/056 (2013.01); A61B 2018/0016 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/0212 (2013.01); A61B 2018/142 (2013.01); A61B 2018/1435 (2013.01); A61B 2018/1475 (2013.01); A61B 2018/1861 (2013.01); A61F 2007/126 (2013.01); A61N 1/3605 (2013.01); A61N 2007/0043 (2013.01); A61N 7/022 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A microsurgical instrument, comprising:
an elongate member defining a longitudinal axis, and having proximal and distal ends, the elongate member configured for passage within a lumen of a subject, the elongate member including a biasing segment configured to at least partially engage an internal wall portion defining the lumen;
one or more electrodes configured to apply stimulation to a target neural structure within or adjacent the lumen;
one or more physiological sensors configured to emit a signal representative of physiological data of the target neural structure;
one or more connectors at the proximal end of the elongate member;
an array of microcircuits embedded along at least a portion of a length of the elongate member; and
at least one of one or more lead wires and one or more fibers connecting the array of microcircuits with (i) the one or more connectors at the proximal end of the elongate member and (ii) at least one of the one or more electrodes and the one or more physiological sensors at the distal end of the elongate member.