US 12,064,236 B2
Methods, systems, and devices for improved sensors for continuous glucose monitoring
Soroush Hossein Yazdi, Laguna Niguel, CA (US); Melissa Tsang, Sherman Oaks, CA (US); Ellis Garai, Studio City, CA (US); Sadaf S. Seleh, Encino, CA (US); Steven Lai, Granada Hills, CA (US); Luis A. Torres, South Gate, CA (US); Bradley Petkus, Sherman Oaks, CA (US); Xin Heng, Glendale, CA (US); Zhenzhong Sun, Northridge, CA (US); Akhil Srinivasan, Woodland Hills, CA (US); and Tyler R. Wong, Pasadena, CA (US)
Assigned to MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed by MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed on Jun. 11, 2020, as Appl. No. 16/898,941.
Prior Publication US 2021/0386331 A1, Dec. 16, 2021
Int. Cl. A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 5/1486 (2006.01); G16H 20/10 (2018.01)
CPC A61B 5/14532 (2013.01) [A61B 5/1486 (2013.01); A61B 5/4848 (2013.01); A61B 5/7203 (2013.01); G16H 20/10 (2018.01)] 9 Claims
OG exemplary drawing
 
1. A system for continuous glucose monitoring, comprising:
one or more processors; and
one or more processor-readable media storing instructions which, when executed by the one or more processors, causes the system to:
activate a working electrode of a subcutaneously placed glucose sensor, the working electrode configured to generate a first sensor current;
activate a background electrode of the subcutaneously placed glucose sensor, the background electrode configured to generate a second sensor current;
cause a plurality of pulses to be applied to the working electrode and the background electrode to stabilize the glucose sensor;
set the working electrode to a first voltage potential, wherein the working electrode includes a glucose oxidase sensor and the first sensor current generated by the working electrode is affected by exposure of the glucose oxidase sensor to a medication ingested by a user;
set the background electrode to a second voltage potential greater than the first voltage potential, the background electrode having a metallization layer, wherein the second sensor current generated by the background electrode is not affected by exposure of the background electrode to the medication ingested by the user;
receive the first sensor current from the working electrode;
receive the second sensor current from the background electrode;
generate a sensor glucose value based on the first sensor current;
determine an electrochemical impedance spectroscopy (EIS) impedance value of the background electrode;
input the first sensor current and the second sensor current into a mathematical model that calculates a new value of the first sensor current based at least in part on the EIS impedance value of the background electrode; and
adjust the sensor glucose value based on the new value of the first sensor current calculated by the mathematical model.