CPC A61B 5/0004 (2013.01) [A61B 5/0066 (2013.01); A61B 5/0084 (2013.01); A61B 5/0261 (2013.01)] | 16 Claims |
1. An optical measurement system, comprising:
an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure;
an optical detector configured for detecting the physiological-encoded signal light
a processor configured for acquiring an initial time-of-flight (TOF) profile derived from the physiological-encoded signal light, the initial TOF profile having a shot noise variance, the processor further configured for applying a weighting function to the initial TOF profile to generate a weighted TOF profile that has a decreased shot noise variance, the processor further configured for processing the weighted TOF profile by reducing the weighted TOF profile to a single index value indicative of the one state of the physiological activity, and identifying one of a plurality of states of a physiological activity in the anatomical structure based on the single index value.
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