US 12,064,167 B2
Method of treating or alleviating erectile dysfunction
Gaojun Teng, Nanjing (CN); Yonghua Dong, Shanghai (CN); Huaqing Yin, Shanghai (CN); Qi Zhang, Nanjing (CN); Meijun Shen, Shanghai (CN); and Jiulin Guo, Shanghai (CN)
Assigned to Shanghai Golden Leaf Medtech Co., Ltd., Shanghai (CN)
Filed by Gaojun Teng, Nanjing (CN); Yonghua Dong, Shanghai (CN); Huaqing Yin, Shanghai (CN); Qi Zhang, Nanjing (CN); Meijun Shen, Shanghai (CN); and Jiulin Guo, Shanghai (CN)
Filed on Sep. 17, 2019, as Appl. No. 16/574,039.
Application 16/574,039 is a continuation in part of application No. 16/147,789, filed on Sep. 30, 2018, abandoned.
Application 16/147,789 is a continuation in part of application No. 15/501,662, abandoned, previously published as PCT/CN2015/081584, filed on Jun. 16, 2015.
Claims priority of application No. 201410381377.6 (CN), filed on Aug. 5, 2014; application No. 201410554508.6 (CN), filed on Oct. 17, 2014; and application No. 201910798477.1 (CN), filed on Aug. 27, 2019.
Prior Publication US 2020/0008871 A1, Jan. 9, 2020
Int. Cl. A61B 18/14 (2006.01); A61N 1/05 (2006.01); A61N 1/40 (2006.01); A61B 18/00 (2006.01); A61M 25/00 (2006.01)
CPC A61B 18/1492 (2013.01) [A61N 1/05 (2013.01); A61N 1/403 (2013.01); A61B 2018/00083 (2013.01); A61B 2018/00267 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00678 (2013.01); A61B 2018/00821 (2013.01); A61B 2018/1467 (2013.01); A61M 2025/0036 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method of treating or alleviating erectile dysfunction in a patient comprising (1) placing multiple electrodes of a catheter apparatus within a segment of an internal iliac artery of the patient and against a blood vessel wall of the internal iliac artery by percutaneous transluminal intravascular access; (2) adhering a surface electrode on an external surface such as skin of the patient; and (3) releasing radiofrequency energy through at least one of the multiple electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues; wherein the catheter apparatus comprises: an elongated shaft having a proximal portion and a distal portion; a carrier carrying at least one therapeutic assembly, wherein the carrier is located at, or proximate to, the distal portion of the elongated shaft, and wherein the at least one therapeutic assembly comprises the multiple electrodes for intravascular treatment; wherein the carrier is configured to vary between a delivery configuration and a deployed configuration: wherein the distal portion of the shaft is configured for intravascular delivery of the carrier: wherein the carrier comprises m (m is at least two) right-handed wire helixes and n (n is at least two) left-handed wire helixes that are plainly or bi-axially woven into each other: wherein the carrier comprises at least one interstice that is defined by four wire helix segments from two of the immediately adjacent at least two right-handed wire helixes and two of the immediately adjacent at least two left-handed wire helixes that are plainly or bi-axially woven into each other; wherein said at least one therapeutic assembly wraps around at least one of said four wire helix segments to stabilize said at least one interstice, to maintain structural integrity of the carrier, and to prevent tangling of the m right-handed wire helixes and the n left-handed wire helixes, when the carrier is being distorted intravascularly, wherein at least two of the m right-handed wire helixes and at least two of the n left-handed wire helixes are made from two single wires each having a first portion of right-handed wire helix and a second portion of left-handed wire helix by folding or bending a point of the single wire between the first portion and the second portion at an angle of from about 160 to 180 degree; wherein the catheter apparatus further comprises a multi-lumen bundler, wherein the multi-lumen bundler has a cylinder body, and a number of lumens pass axially through the cylinder body along the longitudinal axis of the cylinder body; wherein said two single wires each having a first portion of right-handed wire helix and a second portion of left-handed wire helix are inserted into, and pass through, a same lumen selected from said a number of lumens; and wherein the first portion of right-handed wire helix of each of said two single wires is inserted into and passes through one of said a number of lumens, the second portion of left-handed wire helix of said each one of said two single wires is inserted into and passes through another of said number of lumens, and said each one of said two single wires is permanently glued and fixed to the multi-lumen bundler with a liquid adhesive material filled into or dropped into the lumens and solidified thereafter.