CPC C07K 16/2818 (2013.01) [A61K 45/06 (2013.01); A61K 47/6851 (2017.08); C07K 16/2803 (2013.01); C07K 16/2878 (2013.01); C12N 15/85 (2013.01); A61K 2039/507 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01)] | 21 Claims |
1. An antibody or an antigen-binding fragment thereof that binds to LAG-3, the antibody comprising a heavy chain variable region and a light chain variable region, wherein the heavy chain variable region comprises HCDR1, HCDR2, HCDR3, and the light chain variable region comprises LCDR1, LCDR2 and LCDR3, wherein the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 comprises or consists of the amino acid sequences respectively represented by
(i) SEQ ID NO: 4, 7, 9, 11, 13 and 16;
(ii) SEQ ID NO: 1, 5, 8, 11, 13 and 14;
(iii) SEQ ID NO: 2, 6, 9, 11, 13 and 15; or
(iv) SEQ ID NO: 3, 7, 10, 12, 13, and 16.
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