	US 12,392,786 B2
	Methods for diagnosing Huntington's Disease
Laura Ranum, Gainesville, FL (US); and Monica Banez Coronel, Gainesville, FL (US)
Assigned to University of Florida Research Foundation, Incorporated, Gainesville, FL (US)
Filed by University of Florida Research Foundation, Incorporated, Gainesville, FL (US)
Filed on Apr. 10, 2023, as Appl. No. 18/297,883.
Application 18/297,883 is a continuation of application No. 16/695,717, filed on Nov. 26, 2019, abandoned.
Application 16/695,717 is a continuation of application No. 15/577,995, granted, now 10,509,045, previously published as PCT/US2016/034738, filed on May 27, 2016.
Claims priority of provisional application 62/168,695, filed on May 29, 2015.
Prior Publication US 2023/0288434 A1, Sep. 14, 2023
Int. Cl. G01N 33/68 (2006.01); C07K 16/18 (2006.01); C12N 15/113 (2010.01)

CPC G01N 33/6896 (2013.01) [C07K 16/18 (2013.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); G01N 2333/46 (2013.01); G01N 2800/2835 (2013.01)]

19 Claims

1. A method for producing an antibody or fragment thereof, the method comprising: administering to a non-human subject or cell a peptide antigen consisting of the amino acid sequence set forth in SEQ ID NO: 19 to produce an anti-repeat-associated non-ATG (RAN) protein antibody or fragment thereof and isolating the anti-RAN protein antibody or fragment thereof, wherein the isolated anti-RAN antibody or fragment thereof is a humanized antibody or a chimeric antibody.