	US 12,391,911 B2
	Adherent cell culture substrate sampling device
Vesa Turkki, Kuopio (FI); and Nigel Parker, Chinnor (GB)
Assigned to TRIZELL LTD., Chinnor (GB)
Filed by TRIZELL LTD., Chinnor (GB)
Filed on Feb. 14, 2024, as Appl. No. 18/441,106.
Application 18/441,106 is a continuation of application No. 15/763,123, granted, now 11,932,843, previously published as PCT/IB2017/057008, filed on Nov. 9, 2017.
Claims priority of provisional application 62/419,613, filed on Nov. 9, 2016.
Prior Publication US 2024/0263125 A1, Aug. 8, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C12M 1/12 (2006.01); C12M 1/00 (2006.01); C12M 3/00 (2006.01); C12N 5/00 (2006.01)

CPC C12M 37/04 (2013.01) [C12M 21/08 (2013.01); C12M 23/14 (2013.01); C12M 23/28 (2013.01); C12M 25/00 (2013.01); C12M 25/02 (2013.01); C12M 29/00 (2013.01); C12N 5/0068 (2013.01)]

6 Claims

1. An apparatus for aseptically obtaining a sample of a solid substrate for adherent cell culture contained in the interior of a bioreactor container, the apparatus comprising:

a sampling device housing having a sampling device housing exterior and a sampling device housing interior, the sampling device housing configured to be disposable on the port of an adherent cell culture bioreactor so that the sampling device housing interior can be in aseptic communication with the bioreactor container interior via the port,

the sampling device housing interior housing a solid substrate sampling device configured to obtain a sample of solid substrate for adherent cell culture contained in the bioreactor container interior,

the solid substrate sampling device disposed in the sampling device housing interior whereby the solid substrate sampling device can aseptically obtain a sample of solid substrate for adherent cell culture contained in the interior of the bioreactor container.