US 12,391,789 B2
Ophthalmic devices containing localized grafted networks and processes for their preparation and use
Brian Aitken, Jacksonville, FL (US); Charles W. Scales, St. Augustine, FL (US); Joe M. Wood, Jacksonville, FL (US); and Michael F. Widman, Jacksonville, FL (US)
Assigned to Johnson & Johnson Vision Care, Inc., Jacksonville, FL (US)
Filed by Johnson & Johnson Vision Care, Inc., Jacksonville, FL (US)
Filed on Aug. 29, 2023, as Appl. No. 18/457,455.
Application 18/457,455 is a division of application No. 17/318,335, filed on May 12, 2021, granted, now 11,780,953.
Application 17/318,335 is a continuation of application No. 16/239,603, filed on Jan. 4, 2019, granted, now 11,034,789, issued on Jun. 15, 2021.
Claims priority of provisional application 62/623,789, filed on Jan. 30, 2018.
Prior Publication US 2023/0406995 A1, Dec. 21, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C08G 18/61 (2006.01); B29D 11/00 (2006.01); C08F 290/06 (2006.01); C08G 18/04 (2006.01); C08G 18/62 (2006.01); C08L 51/08 (2006.01); G02B 1/04 (2006.01); G02C 7/04 (2006.01)
CPC C08G 18/61 (2013.01) [B29D 11/00067 (2013.01); B29D 11/00076 (2013.01); C08F 290/068 (2013.01); C08G 18/04 (2013.01); C08G 18/6225 (2013.01); C08L 51/085 (2013.01); G02B 1/043 (2013.01); G02C 7/04 (2013.01); C08G 2270/00 (2013.01)] 10 Claims
 
1. A process for making an ophthalmic device, the process comprising:
(a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker;
(b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator;
(c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and
(d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the grafting composition polymerizes therein with the crosslinked substrate network.