US 12,391,735 B2
Polypeptide having effect of inhibiting proliferation of leukemia cells
Jiang Zhu, Nanjing (CN); An Zhong, Nanjing (CN); and Meiqi Lv, Nanjing (CN)
Appl. No. 17/299,292
Filed by NANJING FENGRUI BIOTECHNOLOGY CO., LTD, Nanjing (CN)
PCT Filed Mar. 7, 2019, PCT No. PCT/CN2019/077271
§ 371(c)(1), (2) Date Jun. 2, 2021,
PCT Pub. No. WO2020/147176, PCT Pub. Date Jul. 23, 2020.
Claims priority of application No. 201910036210.9 (CN), filed on Jan. 15, 2019.
Prior Publication US 2025/0084138 A1, Mar. 13, 2025
Int. Cl. C07K 14/47 (2006.01); A61P 35/02 (2006.01); C07K 1/06 (2006.01); C07K 1/16 (2006.01); A61K 38/00 (2006.01)
CPC C07K 14/4703 (2013.01) [A61P 35/02 (2018.01); C07K 1/061 (2013.01); C07K 1/16 (2013.01); A61K 38/00 (2013.01)] 2 Claims
 
1. A polypeptide having an effect of inhibiting the proliferation of leukemia cells, wherein the polypeptide consists of 37 amino acids, with the amino acid sequence of
SEQ ID NO: 1
Lys-Glu-Ser-Met-Asp-Ala-Asn-Lys-Pro-Thr-Lys-Asn-
 
Leu-Pro-Leu-Lys-Lys-Ile-Pro-Cys-Lys-Thr-Ser-Ala-
 
Pro-Ser-Gln-Ser-Phe-Phe-Ala-Arg-Asp-Asn-Thr-Ala-
 
Asn.