US 12,391,693 B2
Solid polymorphs of a FLNA-binding compound and its hydrochloride salts
Michael Zamloot, Austin, TX (US); Lindsay Burns Barbier, Austin, TX (US); and Shawn Anthony Kucera, Cedar Park, TX (US)
Assigned to Cassava Sciences, Inc., Austin, TX (US)
Filed by Cassava Sciences, Inc., Austin, TX (US)
Filed on Nov. 21, 2024, as Appl. No. 18/955,947.
Application 17/850,198 is a division of application No. 16/798,041, filed on Feb. 21, 2020, granted, now 11,370,791, issued on Jun. 28, 2022.
Application 18/955,947 is a continuation of application No. 18/802,950, filed on Aug. 13, 2024.
Application 18/802,950 is a continuation of application No. 17/850,198, filed on Jun. 27, 2022, granted, now 12,065,440, issued on Aug. 20, 2024.
Claims priority of provisional application 62/808,609, filed on Feb. 21, 2019.
Prior Publication US 2025/0084083 A1, Mar. 13, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 471/10 (2006.01)
CPC C07D 471/10 (2013.01) [C07B 2200/13 (2013.01)] 21 Claims
 
1. Crystalline 1-benzyl-8-methyl-1,4,8-triazaspiro-[4.5]-decan-2-one dihydrochloride monohydrate, Crystalline Form 1.