US 12,391,670 B2
Functionalized aminotriazines
Werner Neidhart, Villigen (CH); and Denis Bucher, Villigen (CH)
Assigned to LEADXPRO AG, Villigen (CH)
Appl. No. 17/287,467
Filed by LEADXPRO AG, Villigen (CH)
PCT Filed Oct. 23, 2019, PCT No. PCT/EP2019/078789
§ 371(c)(1), (2) Date Apr. 21, 2021,
PCT Pub. No. WO2020/083957, PCT Pub. Date Apr. 30, 2020.
Claims priority of application No. 18202231 (EP), filed on Oct. 24, 2018.
Prior Publication US 2021/0395225 A1, Dec. 23, 2021
Int. Cl. C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01)
CPC C07D 401/14 (2013.01) [C07D 401/04 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01)] 5 Claims
 
1. A compound of formula I

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt or hydrate thereof, wherein said compound is a compound of formula Ia, formula Ib or formula Ic, wherein R2 is selected from hydrogen, C1-C8 alkyl, halogen and C1-C8 alkoxy:

OG Complex Work Unit Chemistry
wherein said Ra is selected from the group consisting of:

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry
wherein said R1 is selected from hydrogen, halogen, C1-C2alkyl, C1-C2haloalkyl, C1-C2alkoxy, C1-C2hydroxyalkyl and C1-C2alkoxyalkyl.