| CPC B65D 1/40 (2013.01) [C03C 3/078 (2013.01); C03C 3/091 (2013.01); B65D 2575/52 (2013.01)] | 20 Claims |

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1. A glass tube for pharmaceutical containers, comprising:
an inner surface at an inner diameter and an outer surface with an outer diameter;
a first end defining a first closed end;
a second end defining a second closed end;
a first location 400 mm from the first end;
a first intermediate location 15 mm from the first end; and
a ventilation hole at a first vicinity, the first vicinity being between the first intermediate location and the first location,
wherein the inner surface in the first vicinity has measurable first ToF-SIMS signals, the first ToF-SIMS signals including an Na2F+ signal and an 30Si+ signal,
wherein the inner surface has an area in the first vicinity that is 36 mm2 or less,
wherein the first vicinity has a ratio of an integrated Na2F+ signal to an integrated 30Si+ signal of at least 0.10, and
wherein the integrated Na2F+ signal and the integrated 30Si+ signal are integrated over a depth of 100 nm.
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