US 12,390,646 B2
Implantable medical devices
Nicholas Nesbitt, Minneapolis, MN (US); Kevin Verzal, Lino Lakes, MN (US); David Dieken, Minneapolis, MN (US); John Rondoni, Plymouth, MN (US); Christopher Thorp, Minneapolis, MN (US); and Douglas Murphy, Golden Valley, MN (US)
Assigned to INSPIRE MEDICAL SYSTEMS, INC., Golden Valley, MN (US)
Filed by INSPIRE MEDICAL SYSTEMS, INC., Golden Valley, MN (US)
Filed on Dec. 1, 2021, as Appl. No. 17/539,916.
Claims priority of provisional application 63/120,313, filed on Dec. 2, 2020.
Prior Publication US 2023/0166113 A1, Jun. 1, 2023
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01)
CPC A61N 1/36178 (2013.01) [A61N 1/05 (2013.01); A61N 1/3611 (2013.01); A61N 1/36192 (2013.01); A61N 1/36196 (2013.01)] 26 Claims
OG exemplary drawing
 
1. An implantable medical device comprising:
an output signal driver configured to generate stimulation pulses to stimulate a nerve within a patient;
a first electrode coupled to the output signal driver;
a second electrode coupled to the output signal driver; and
a controller configured to control the output signal driver to selectively apply between the first electrode and the second electrode a first pulse train to stimulate the nerve within the patient and a second pulse train to stimulate the nerve within the patient,
wherein the first electrode and the second electrode are arranged in an electrode cuff configured to generate unidirectional propagation of action potentials towards efferent terminals,
wherein each pulse of the second pulse train follows a pulse of the first pulse train by an interval, and
wherein the interval is adjustable to change the relative excitability of the nerve within the patient.