US 12,390,577 B2
System for safe radioisotope preparation and injection
Peter Larsen, Vaerlose (DK); Martin Stenfeldt, Vedaek (DK); and Rune Wiik Kristensen, Hinnerup (DK)
Assigned to MedTrace Pharma A/S, Hørsholm (DK)
Appl. No. 15/738,032
Filed by MedTrace Pharma A/S, Hørsholm (DK)
PCT Filed Jun. 20, 2016, PCT No. PCT/EP2016/064221
§ 371(c)(1), (2) Date Dec. 19, 2017,
PCT Pub. No. WO2016/203055, PCT Pub. Date Dec. 22, 2016.
Claims priority of application No. 15172904 (EP), filed on Jun. 19, 2015.
Prior Publication US 2018/0296750 A1, Oct. 18, 2018
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 5/00 (2006.01); A61B 6/03 (2006.01); A61B 6/42 (2024.01); A61M 5/14 (2006.01); A61M 5/36 (2006.01); A61M 39/22 (2006.01); F16K 11/085 (2006.01); G21G 1/00 (2006.01); G21G 1/10 (2006.01)
CPC A61M 5/007 (2013.01) [A61B 6/4258 (2013.01); A61M 5/00 (2013.01); A61M 5/14 (2013.01); A61M 5/1407 (2013.01); A61M 5/36 (2013.01); A61M 5/365 (2013.01); A61M 39/22 (2013.01); A61M 39/223 (2013.01); F16K 11/085 (2013.01); F16K 11/0853 (2013.01); G21G 1/10 (2013.01); A61B 6/037 (2013.01); A61M 2039/226 (2013.01); A61M 2039/229 (2013.01); A61M 2205/33 (2013.01); A61M 2205/3341 (2013.01); A61M 2205/3379 (2013.01); G21G 2001/0094 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A regulating means for a system for preparing and injecting H215O to a patient for use in Positron Emission Tomography, the regulating means comprising;
a first saline feed for supplying a saline supply for preparing a saline solution of H215O,
a loop element having a predefined volume for collecting a first bolus of said saline solution of H215O for delivery to the patient, the first bolus having the predefined volume of the loop element and a desired radioactivity concentration, an entirety of the loop element being located upstream from and connected to a patient line configured to be in fluid communication with the patient,
a second saline feed for supplying a second bolus of saline,
an injection means including a collecting element having a predefined volume for collecting the second bolus of saline from said second saline feed, the second bolus having the predefined volume of the collecting element, the injection means and the second saline feed being located upstream of the entirety of the loop element relative to the patient line, the injection means being configured to inject said second bolus at a predefined speed into the loop element, so that the second bolus pushes the entire predefined volume of the first bolus from the loop element directly into the patient line,
wherein said injection speed and the predefined volume of the second bolus regulates the injection profile of the first bolus.