US 12,390,570 B2
Localized therapy delivery and local organ protection
Pramote Hochareon, Vadnais Heights, MN (US)
Assigned to NirvaMed, Inc., Bloomington, MN (US)
Filed by NirvaMed, Inc., Bloomington, MN (US)
Filed on Oct. 12, 2021, as Appl. No. 17/499,210.
Application 17/499,210 is a continuation of application No. 16/262,552, filed on Jan. 30, 2019, granted, now 11,173,239.
Application 16/262,552 is a continuation of application No. 15/054,379, filed on Feb. 26, 2016, granted, now 10,195,333, issued on Feb. 5, 2019.
Application 15/054,379 is a continuation of application No. 14/216,625, filed on Mar. 17, 2014, granted, now 9,308,310, issued on Apr. 12, 2016.
Application 14/216,625 is a continuation in part of application No. 13/576,302, granted, now 9,078,980, issued on Jul. 14, 2015, previously published as PCT/US2011/023471, filed on Feb. 2, 2011.
Claims priority of provisional application 61/800,248, filed on Mar. 15, 2013.
Claims priority of provisional application 61/300,703, filed on Feb. 2, 2010.
Prior Publication US 2022/0023611 A1, Jan. 27, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 1/36 (2006.01); A61M 1/34 (2006.01); A61M 25/00 (2006.01); A61M 25/10 (2013.01); A61M 39/22 (2006.01)
CPC A61M 1/3613 (2014.02) [A61M 1/34 (2013.01); A61M 1/3403 (2014.02); A61M 1/3601 (2014.02); A61M 1/3607 (2014.02); A61M 1/3615 (2014.02); A61M 1/3659 (2014.02); A61M 25/0026 (2013.01); A61M 25/10 (2013.01); A61M 39/22 (2013.01); A61M 2025/0031 (2013.01); A61M 2025/0037 (2013.01); A61M 2025/1052 (2013.01); A61M 2202/0413 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/36 (2013.01); A61M 2230/005 (2013.01); A61M 2230/04 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A delivery system for delivering fluid to a target region of a body, the delivery system comprising:
a catheter apparatus having one or more catheters, the catheter apparatus including:
(i) an occlusion device adapted to selectively substantially occlude a blood flow structure that is fluidically connected to the target region so as to selectively define a circulatory barrier between the target region and a systemic region of the body;
(ii) a channel for conveying fluid along at least one direction of to and from the target region; and
(iii) a target region port of the channel that opens to the target region; and
a fluid management apparatus for supplying fluid through the channel, and fluidically coupling the channel to a systemic port that opens to the systemic region of the body, the fluid management apparatus being capable of conditioning fluid, and recirculating fluid received from the target region as conditioned recirculation fluid to the target region.