US 12,390,568 B2
Medicament preparation and treatment devices, methods, and systems
Goetz Friederichs, Beverly, MA (US); William K. Weigel, Portland, ME (US); Dennis M. Treu, Castle Rock, CO (US); Jeffrey H Burbank, Manchester, MA (US); James M. Brugger, Newburyport, MA (US); Keith David J. Wheeler, Tyngsboro, MA (US); and Scott W. Newell, Ipswich, MA (US)
Filed by NxStage Medical, Inc., Lawrence, MA (US)
Filed on Apr. 29, 2024, as Appl. No. 18/648,525.
Application 18/648,525 is a continuation of application No. 17/511,348, filed on Oct. 26, 2021, granted, now 11,986,582.
Application 17/511,348 is a continuation of application No. 16/575,482, filed on Sep. 19, 2019, granted, now 11,167,069, issued on Nov. 9, 2021.
Application 16/575,482 is a continuation of application No. 15/514,230, granted, now 10,478,544, issued on Nov. 19, 2019, previously published as PCT/US2015/052385, filed on Sep. 25, 2015.
Claims priority of provisional application 62/055,022, filed on Sep. 25, 2014.
Prior Publication US 2024/0277909 A1, Aug. 22, 2024
Int. Cl. A61M 1/16 (2006.01); A61K 31/191 (2006.01); A61M 1/14 (2006.01); A61M 1/36 (2006.01); B01F 21/20 (2022.01); C02F 9/00 (2023.01); F15B 1/04 (2006.01); C02F 1/20 (2023.01); C02F 1/28 (2023.01); C02F 1/42 (2023.01); C02F 1/44 (2023.01); C02F 103/02 (2006.01); C02F 103/04 (2006.01)
CPC A61M 1/1666 (2014.02) [A61K 31/191 (2013.01); A61M 1/1524 (2022.05); A61M 1/154 (2022.05); A61M 1/155 (2022.05); A61M 1/1561 (2022.05); A61M 1/1562 (2022.05); A61M 1/1565 (2022.05); A61M 1/1658 (2013.01); A61M 1/166 (2014.02); A61M 1/362227 (2022.05); A61M 1/36224 (2022.05); A61M 1/36225 (2022.05); A61M 1/362261 (2022.05); A61M 1/362262 (2022.05); A61M 1/362265 (2022.05); B01F 21/20 (2022.01); C02F 9/00 (2013.01); F15B 1/04 (2013.01); A61M 1/1563 (2022.05); A61M 1/362263 (2022.05); A61M 2205/3317 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/502 (2013.01); A61M 2205/6054 (2013.01); A61M 2205/6072 (2013.01); C02F 1/20 (2013.01); C02F 1/283 (2013.01); C02F 1/42 (2013.01); C02F 2001/425 (2013.01); C02F 2001/427 (2013.01); C02F 1/44 (2013.01); C02F 2103/026 (2013.01); C02F 2103/04 (2013.01); C02F 2209/05 (2013.01); C02F 2209/445 (2013.01); F15B 2201/315 (2013.01); Y02A 50/30 (2018.01)] 6 Claims
OG exemplary drawing
 
1. A fluid circuit, comprising:
a planar member having a pattern of uniform fluid channels formed therein, having a water inlet and a generally uniform cross-section, and defining a product solution channel with multiple concentration measurement stations along the product solution channel, each of the multiple concentration measurement stations following a respective one of junctions at which respective solutes are injected into said product solution channel;
each concentration measurement station including an inlet opening in the planar member defining a first passage between a portion of said uniform fluid channels and an expanded fluid flow column;
the expanded fluid flow column having electrodes spaced apart along said expanded fluid flow column;
each concentration measurement station further including an outlet opening in the planar member defining a second passage between a first portion of said uniform fluid channels and the expanded fluid flow column;
the inlet openings and the outlet openings being at opposite ends of the expanded fluid flow column;
the outlet opening leading from the expanded fluid flow column into an expanded section of said uniform fluid channels having a flat face covered by a film, the outlet opening being at an edge of said expanded section;
a return opening opposite said outlet opening leading to a second portion of said uniform fluid channels downstream from said first portion; and
the electrodes having flat external contact surfaces that are parallel to the flat face such that electrical contacts and a temperature probe can be brought into a thermal and electrical contact by moving the fluid circuit in a direction that is perpendicular to said flat face and said flat external contact surfaces relative to electrical contacts and a temperature sensor until the thermal and electrical contact is made.