	US 12,390,502 B2
	Method for stimulating growth of bacteria in the gut microbiota of a mammal
Bertrand Rodriguez, Lambersart (FR)
Assigned to LESAFFRE ET COMPAGNIE, Paris (FR)
Appl. No. 17/425,588
Filed by LESAFFRE ET COMPAGNIE, Paris (FR)
PCT Filed Jan. 22, 2020, PCT No. PCT/EP2020/051537 § 371(c)(1), (2) Date Jul. 23, 2021, PCT Pub. No. WO2020/152229, PCT Pub. Date Jul. 30, 2020.
Claims priority of application No. 19305090 (EP), filed on Jan. 23, 2019.
Prior Publication US 2022/0096580 A1, Mar. 31, 2022
Int. Cl. A61K 36/064 (2006.01); A23C 9/127 (2006.01); A23C 9/20 (2006.01); A23L 31/15 (2016.01); A61K 31/716 (2006.01); A61P 1/12 (2006.01)

CPC A61K 36/064 (2013.01) [A23C 9/127 (2013.01); A23C 9/203 (2013.01); A23L 31/15 (2016.08); A61K 31/716 (2013.01); A61P 1/12 (2018.01)]

23 Claims

1. A method for stimulating growth of a bacterium of the Bacteroidetes phylum in a gut of a mammal, the method comprising:

selecting a mammal in need of stimulated growth of bacteria of the Bacteroidetes phylum in the gut of the mammal;

preparing a yeast product by subjecting a yeast cream to plasmolysis at a temperature between 70° C. and 95° C., treating at 60° C. with a mix of two glucanases and a mix of endo and exo-ribonucleases, centrifuging to obtain an insoluble yeast protein extract, and washing the insoluble yeast protein extract to obtain the yeast product;

administering the yeast product as a prebiotic agent to the mammal; and

stimulating growth of the bacterium of the Bacteroidetes phylum in the gut of the mammal,

wherein the yeast product comprises walls of yeast cells or a fraction thereof.