US 12,390,495 B2
Micronized eggshell membrane particles and the use thereof to promote the healing of wounds
Ralf Schmidt, Oslo (NO); Henri-Pierre Suso, Oslo (NO); and Enda Kenny, Kilkenny (IE)
Assigned to BIOVOTEC AS, Oslo (NO)
Filed by BIOVOTEC AS, Oslo (NO)
Filed on Apr. 19, 2024, as Appl. No. 18/640,949.
Application 18/640,949 is a continuation of application No. 15/522,441, granted, now 11,992,508, previously published as PCT/EP2015/075041, filed on Oct. 28, 2015.
Claims priority of application No. 1419183 (GB), filed on Oct. 28, 2014; application No. 1506504 (GB), filed on Apr. 16, 2015; and application No. 1511476 (GB), filed on Jun. 30, 2015.
Prior Publication US 2025/0082691 A1, Mar. 13, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/57 (2015.01); A61K 9/14 (2006.01); A61L 15/40 (2006.01); A61L 15/60 (2006.01); A61L 26/00 (2006.01); A61L 27/36 (2006.01); A61L 31/00 (2006.01); A61L 31/08 (2006.01); A61P 17/02 (2006.01)
CPC A61K 35/57 (2013.01) [A61K 9/14 (2013.01); A61L 15/40 (2013.01); A61L 15/60 (2013.01); A61L 26/0023 (2013.01); A61L 26/0057 (2013.01); A61L 26/008 (2013.01); A61L 27/3604 (2013.01); A61L 31/005 (2013.01); A61L 31/08 (2013.01); A61P 17/02 (2018.01); A61L 2300/30 (2013.01); A61L 2300/404 (2013.01); A61L 2300/41 (2013.01); A61L 2300/412 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A method of promoting the healing of a non-healing chronic wound, wherein the non-healing chronic wound,
(i) has not healed in 30 days after wound formation, and
(ii) is stalled in the inflammatory stage of wound healing,
wherein said method consists of applying directly to the surface or interior of the non-healing chronic wound a particle consisting of micronized egg shell membrane (ESM) having a mean particle diameter of equal to or less than 80 μm and being essentially insoluble in water at a neutral pH,
wherein the particle is applied to the non-healing chronic wound in the form of a wound dressing, and
wherein the application of the particle to the non-healing chronic wound causes the non-healing chronic wound to progress through the healing stages.