US 12,390,488 B2
Oral articles and methods of use
Hannah C. Cohen, St. Paul, MN (US); Katie F. Wlaschin, St. Paul, MN (US); Yizhong Wang, Woodbury, MN (US); Amanda C. Engler, Woodbury, MN (US); Jie Yang, Woodbury, MN (US); Tiffany T. Ton, Woodbury, MN (US); and Joel D. Oxman, Minneapolis, MN (US)
Assigned to Solventum Intellectual Properties Company, Maplewood, MN (US)
Appl. No. 17/419,527
Filed by Solventum Intellectual Properties Company, Maplewood, MN (US)
PCT Filed Dec. 27, 2019, PCT No. PCT/IB2019/061406
§ 371(c)(1), (2) Date Jun. 29, 2021,
PCT Pub. No. WO2020/136620, PCT Pub. Date Jul. 2, 2020.
Claims priority of provisional application 62/786,359, filed on Dec. 29, 2018.
Prior Publication US 2022/0079976 A1, Mar. 17, 2022
Int. Cl. A61K 8/06 (2006.01); A61K 8/25 (2006.01); A61K 8/92 (2006.01); A61K 9/20 (2006.01); A61K 33/00 (2006.01); A61Q 11/00 (2006.01)
CPC A61K 33/00 (2013.01) [A61K 8/25 (2013.01); A61K 8/922 (2013.01)] 19 Claims
 
1. An article comprising:
an oil phase comprising:
one or more plant-based oil present in an amount from 75 wt-% to 99 wt-%;
fumed silica present in an amount from 0.5 wt-% to 10 wt-%; and
an aqueous phase comprising:
water,
wherein the one or more plant-based oil is a solid at 25° C.,
wherein the article is solid set and homogenous at 25° C. without requiring emulsifiers,
wherein the article is characterized by a homogeneity that is stable upon heating to 45° C. and subsequently cooling to 25° C., and
wherein each wt-% is with respect to the weight of the article.