	US 12,390,486 B2
	Method for treating diastolic heart failure by inhibiting galectin-3
Hani N. Sabbah, Waterford, MI (US)
Assigned to Henry Ford Health System, Detroit, MI (US)
Filed by Henry Ford Health System, Detroit, MI (US)
Filed on Jul. 6, 2021, as Appl. No. 17/367,957.
Application 17/367,957 is a continuation in part of application No. 15/877,733, filed on Jan. 23, 2018, granted, now 11,077,137.
Application 15/877,733 is a continuation of application No. 14/654,140, granted, now 9,907,814, issued on Mar. 6, 2018, previously published as PCT/US2013/077169, filed on Dec. 20, 2013.
Claims priority of provisional application 61/740,018, filed on Dec. 20, 2012.
Prior Publication US 2021/0330694 A1, Oct. 28, 2021
Int. Cl. A61K 31/732 (2006.01)

CPC A61K 31/732 (2013.01)

9 Claims

1. A method for treating heart failure with preserved ejection fraction (HFpEF) in a subject in need thereof, the subject having a left ventricular ejection fraction of greater than 45% before treatment, the method comprising:

administering a therapeutically effective amount of N-acetyl-D-lactosamine (LacNAc) to the subject.