	US 12,390,415 B2
	Method for improving storage stability
Iwao Yamaguchi, Tokyo (JP)
Assigned to SEIKAGAKU CORPORATION, Tokyo (JP)
Appl. No. 17/428,425
Filed by SEIKAGAKU CORPORATION, Tokyo (JP)
PCT Filed Feb. 21, 2020, PCT No. PCT/JP2020/007115 § 371(c)(1), (2) Date Aug. 4, 2021, PCT Pub. No. WO2020/171212, PCT Pub. Date Aug. 27, 2020.
Claims priority of application No. 2019-030416 (JP), filed on Feb. 22, 2019.
Prior Publication US 2022/0105028 A1, Apr. 7, 2022
Int. Cl. A61K 9/08 (2006.01); A61B 17/3205 (2006.01); A61K 9/00 (2006.01); A61K 31/728 (2006.01); A61K 47/20 (2006.01); A61K 47/22 (2006.01); A61B 17/00 (2006.01)

CPC A61K 9/0019 (2013.01) [A61B 17/32056 (2013.01); A61K 9/08 (2013.01); A61K 31/728 (2013.01); A61K 47/20 (2013.01); A61K 47/22 (2013.01); A61B 2017/00269 (2013.01); A61B 2017/00681 (2013.01); A61B 2017/00898 (2013.01)]

16 Claims

1. A method for improving the storage stability of a submucosal injection material comprising hyaluronic acid, comprising adding a dye to the submucosal injection material,

wherein the dye is indigo carmine, and

an added amount of the indigo carmine is 0.004% (w/v) or less.