	US 12,390,276 B2
	Spinal implants and surgical procedures with reduced subsidence, and associated systems and methods
Jeremy Winston, San Diego, CA (US); Alexander Roeca, San Diego, CA (US); Elliot Calderon, Carlsbad, CA (US); Sydnee Hyman, San Diego, CA (US); and Niall Patrick Casey, Carlsbad, CA (US)
Assigned to Carlsmed, Inc., Carlsbad, CA (US)
Filed by Carlsmed, Inc., Carlsbad, CA (US)
Filed on Nov. 1, 2022, as Appl. No. 17/978,673.
Claims priority of provisional application 63/274,135, filed on Nov. 1, 2021.
Prior Publication US 2023/0138162 A1, May 4, 2023
Int. Cl. A61B 34/10 (2016.01)

CPC A61B 34/10 (2016.02) [A61B 2034/104 (2016.02); A61B 2034/105 (2016.02)]

54 Claims

1. A computer-implemented method for providing patient-specific medical care, the method comprising:

receiving patient data for a patient, the patient data including one or more images of the patient's spinal region showing the patient's native anatomical configuration;

creating a virtual model of the spinal region showing the patient's native anatomical configuration;

determining a corrected anatomical configuration of the patient's spinal region;

updating the virtual model of the spinal region to illustrate the corrected anatomical configuration;

designing one or more patient-specific intervertebral implants based on the updated virtual model;

before manufacturing the one or more patient-specific intervertebral implants, predicting at least one of a probability that subsidence will occur and/or a magnitude of expected subsidence of the one or more patient-specific intervertebral implants, wherein the predicting is based at least in part on one or more mechanical properties of the patient's spinal region and/or one or more properties of the intervertebral implants; and

in response to the predicted probability that subsidence will occur and/or the magnitude of expected subsidence being less than a predetermined threshold, generating fabrication instructions for making the one or more patient-specific intervertebral implants.